Welcome to Sagiv Shifman Lab

News

New Project! A four-year project to study a mouse model of autism is funded by the Israel Science Foundation

New Paper! Widespread allelic heterogeneity in complex traits. American Journal of Human Genetics [The project is a collaboration with the ZarLab]

New Paper! Varying Intolerance of Gene Pathways to Mutational Classes Explain Genetic Convergence across Neuropsychiatric Disorders. Cell Reports

New Preprint! Profiling adaptive immune repertoires across multiple human tissues by RNA Sequencing. [The project is a collaboration with the ZarLab]

New Paper! Discovering SNPs Regulating Human Gene Expression Using Allele Specific Expression from RNA-Seq Data. Genetics [The project is a collaboration with the ZarLab]

New Preprint! Dumpster diving in RNA-sequencing to find the source of every last read [The project is a collaboration with the ZarLab]

New Paper! Transcriptional dynamics in colorectal carcinogenesis: new insights into the role of c-Myc and miR-17 in benign to cancer transformation. Cancer Research

[The project is a collaboration with the lab of Batsheva Kerem]

New Paper! Bias towards large genes in autism. Nature

New Paper! Chromatin regulators, phenotypic robustness and autism risk. Front. Genet.

New Paper! Allelic expression analysis in the brain suggests a role for heterogeneous insults affecting epigenetic processes in autism spectrum disorders. Human Molecular Genetics

New Project! A three-year project to study the genetics of childhood onset schizophrenia is funded by The National Institute for Psychobiology in Israel

[The project is a collaboration with Yoav Kohn]

New Project! A three-year project to study autism risk gene in flys is funded by the Legacy Heritage Fund program of the Israel Science Foundation

[The project is a collaboration with Sebastian Kadener]

Predoctoral Fellowship! Eyal Ben-David received the highly competitive Weatherstone Predoctoral Fellowship from Autism Speaks

Prize! Sagiv Shifman will be awarded the prestigious Krill Prize from the Wolf Foundation for excellence in scientific research

New Paper! Combined analysis of exome sequencing points toward a major role for transcription regulation during brain development in autism. forthcoming in Molecular Psychiatry

[Highlighted by the Simons Foundation Autism Research Initiative]

New Project! A five-year project on a gene contributing to autism risk is funded by the Israel Science Foundation

New Paper! Fine-scale map of recombination rates and hotspots in the mouse genome. GENETICS

New Paper! Neurogenomic evidence for a shared mechanism of the antidepressant effects of exercise and chronic fluoxetine in mice. PLoS ONE [The project is a collaboration with Guo-Jen Huang]

New Paper! Networks of neuronal genes affected by common and rare variants in autism spectrum disorders. PLoS Genetics

[Highlighted by the Simons Foundation Autism Research Initiative]

New Paper! Identification of a functional rare variant in autism using genome-wide screen for monoallelic expression. Human Molecular Genetics